Clayton, MO vs Wentzville, MO

The cost of living difference between Clayton, MO and Wentzville, MO is dramatic. Wentzville is 54.3% cheaper than Clayton, a gap that translates to thousands of dollars per year in household expenses. Clayton has a cost index of 149 while Wentzville sits at 96, making this one of the more striking comparisons on our site. Relocating between these cities would require a serious reassessment of budget and lifestyle expectations.

On the housing front, median rent in Clayton is $1,648/month compared to $1,264/month in Wentzville — a 30% difference. Home values follow the same pattern: Wentzville is more affordable at $302,700 median vs $799,200.

Median household income in Clayton is $128,898 compared to $111,409 in Wentzville (+15.7%). Clayton does offer higher incomes, but the salary premium barely offsets the higher cost of living, leaving residents with a tighter budget. Looking at affordability, residents of Clayton spend roughly 15.3% of their income on rent, more than the 13.6% in Wentzville.